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Notably, depression is more common in pre-symptomatic HD gene carriers and can manifest up to 10 years prior to the onset of motor symptoms (Duff et al

Within this broad category of diffuse lung diseases, IPF belongs to the subgroup known as idiopathic interstitial pneumonia (IIP)

1.1 Glutathione peroxidase Glutathione peroxidase (GPx) an mammalian enzyme, contains selenocysteine residue in its active site, For the last four decades, an extensive research has been carried out on the mammalian antioxidant enzymes GPx [34]

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however, the 5-year survival rate for patients with advanced OC remains low (49%, 2022) due to tumor heterogeneity, lack of reliable early diagnostic methods and the high incidence of chemotherapy resistance