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Eur Respir J 24 : 994999 Balzar S, Chu HW, Strand M, Wenzel S 2005 Relationship of small airway chymase-positive mast cells and lung function in severe asthma

Extrinsic skin aging expedites aging through environmental factors, causing thickening of the epidermis, decreased proliferation of basal cells, collagen downregulation, and increased oxidative stress [81]

Other manifestations, such as Marburg disease, Schilders disease and Bals concentric sclerosis are mostly understood as specific variants of those diseases ( As already stated, the clinical differentiation between these diseases occurs through lesion topography, disease course and, in certain cases, as NMOSD and MOGAD, by a biological biomarker

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