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In vitro studies on human mononuclear cells also showed that alogliptin (0.5, 1 and 5 nM) treatment for 24 h exhibited a decrease in TLR-4 mediated increase in IL-1 and IL-6 [55]

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Furthermore, its ability to regulate glycemic and lipid profiles vis--vis to maintain tissue integrity, suggests a comprehensive role in cardiovascular risk reduction

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Consequently, the motif-based isotopologue pattern similarity networking is more likely to connect these metabolites

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Sedlak J

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