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Furthermore, you might simply be allergic to an ingredient in the supplement
Bardoxolone methyl is a synthetic triterpenoid, which is more potent than sulforaphane and is effective in a cigarette smoke-exposed mouse model of COPD [124]

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Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

Am J Physiol Cell Physiol 301: C336-C346