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Abstract The incidence of gastrointestinal disorders (GID) and cancers is escalating all over the world

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They are reversibly shuttled along a chain of donoracceptor groups provided by glutamate and aspartate residues and by the entrained water, which together act as a proton wire

Administered at 50 mg/kg, three times weekly for 3 months, ERD upregulated GPX4 and downregulated ACSL4 and TfR1, reducing oxidative stress and iron accumulation

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