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Statistical analyses Statistical analyses were performed using non-parametric Mann-Whitney or Kruskal-Wallis test in GraphPad Prism 8.0.1 software (GraphPad, USA)
ERs can also regulate gene expression without directly interacting with DNA by influencing other transcription factors through their binding to co-regulatory proteins, as in the case with AP-1 complex 9

Ahmed et al., 2020)

The mammalian GH, released from the anterior pituitary gland, is a major driver of somatic growth

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