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188 These findings supported oxidative stress as a feature of AATD contributing to the risk of disease development late in life

Se-dependent enzymes include DIO1, which is expressed in the kidneys and liver, and DIO2, present in the brain and brown adipose tissue, among other organs [27]

Emerging therapeutic targets including PRL3 and L1CAM demonstrate promising anti-metastatic potential, highlighting critical avenues for intervention (118)

Treasure Island (FL): StatPearls Publishing (2025)

PMID: 31201471 Antiviral Res 2026 Jun:250:106417
