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In placebo-controlled trials for type 2 diabetes mellitus (T2DM), semaglutide injection 0.5 and 1 mg resulted in a mean increase in heart rate of 2 to 3 bpm

10.1016/j.abb.2010.11.009 Songisepp E, Kals J, Kullisaar T, Mndar R, Hutt P, Zilmer M, Mikelsaar M: Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers

Zhou S, Wu C, Shen P, Zhou L, Wang W, Lv K, Wei C, Li G, Ma D, Xue W

The increased toxicity of DCVHC relative to DCVC is presumably due to the fact that both compounds generate a toxic reactive sulfur-containing fragment following an elimination reaction