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10.1053/j.gastro.2010.11.005 154 PeiG.KiefferB

Oxford textbook of clinical hepatology

Moreover, CF airway inflammation is due to an excessive neutrophil recruitment, triggered by extrinsic and intrinsic factors, and by an imbalance between reduced concentrations of anti-inflammatory molecules (IL-10, lipoxins, chemotaxis inhibitors, and neutrophil activators) and higher levels of pro-inflammatory proteins (calprotectin)

Furthermore, bicyclol and glycyrrhizin prevent ferroptosis-induced liver and brain injury, respectively, by activating the GPX4 pathway in vivo [194,195]

Design of small molecule autophagy modulators: a promising druggable strategy
