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10.1053/j.gastro.2010.11.005 154 PeiG.KiefferB

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Oxford textbook of clinical hepatology

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Moreover, CF airway inflammation is due to an excessive neutrophil recruitment, triggered by extrinsic and intrinsic factors, and by an imbalance between reduced concentrations of anti-inflammatory molecules (IL-10, lipoxins, chemotaxis inhibitors, and neutrophil activators) and higher levels of pro-inflammatory proteins (calprotectin)

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Furthermore, bicyclol and glycyrrhizin prevent ferroptosis-induced liver and brain injury, respectively, by activating the GPX4 pathway in vivo [194,195]

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Design of small molecule autophagy modulators: a promising druggable strategy

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