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M., de Ridder, D

Collectively, these findings suggest that chronic infection exacerbates age-related immune dysregulation

Supporting this evidence, the presence of a long allele in a (GT) n microsatellite polymorphism in Hmox-1 gene promoter leading to decreased expression of HO-1, gives rise to a pronounced risk and higher susceptibility to develop autoimmune disease, such systemic lupus erythematosus (87)

Circulation 2023;147:24253

Mol Psychiatry 25:12861300
