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Stress, Fatigue, and Emotional State Cortisol, the stress hormone, can elevate BAC by constricting blood vessels, slowing alcohol absorption, and increasing distribution within the body

Interestingly, ursodeoxycholic acid, the only treatment approved by the Food and Drug Administration for the treatment of primary biliary cirrhosis, a chronic cholestatic disorder, was shown to prevent the fall in GCL expression during chronic cholestasis (Serviddio et al., 2004) and increase GCL expression in cultured rat hepatocytes (Mitsuyoshi et al., 1999)

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