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26 CostaC.StruysE.BootsmaA.Ten BrinkH.DorlandL.De AlmeidaI

Refined carbohydrates, artificial sweeteners and processed food can promote harmful gut organisms and lead to inflammation in the gut and breakdown in the intestinal barrier "leaky gut"

On the one hand, high expression of lysine (K)-specific demethylase 6B (KDM6B, also known as JMJD3) activates p16/INK4a gene transcription and promotes oncogene-induced senescence [109], while at the same time down-regulating the expression of C/EBP, which increases the invasiveness of pancreatic ductal adenocarcinoma cells (PDAC) cells [110]

Glibert, P
