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At 6 to 8 weeks, enough time has passed to detect early metabolic responses while still allowing course correction before 3 months of cumulative exposure

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When combined with hyaluronic acid, effects were even more pronounced, with animals showing better cartilage structure preservation and shorter periods of lameness

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Cyanocobalamin, vitamin B12 preparations containing benzyl alcohol should be avoided in premature neonates because benzyl alcohol has been associated with gasping syndrome, a potentially fatal condition characterized by metabolic acidosis and CNS, respiratory, circulatory, and renal dysfunction