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We believe these data underscore the potential of CagriSema to address unmet medical needs in obesity and support long-term disease management." The NDA is based on results from REDEFINE 1, a 68-week, phase 3, randomized, double-blind, placebo-and active-controlled trial that evaluated the efficacy and safety of once-weekly CagriSema compared to semaglutide 2.4 mg alone, cagrilintide 2.4 mg alone, or placebo, all as an adjunct to lifestyle intervention in 3,417 adults with obesity (BMI 30 kg/m 2 ) or overweight (BMI 27 kg/m 2 ) with one or more obesity-related complications and without diabetes, and REDEFINE 2, a double-blind, randomized, placebo-controlled, 68-week, phase 3 trial that evaluated the efficacy and safety of once-weekly CagriSema versus placebo, as an adjunct to lifestyle intervention in 1,206 adults with type 2 diabetes and either obesity (BMI 30 kg/m 2 ) or overweight (BMI 27 kg/m 2 )

All cells were grown at 37 C in a 5% CO 2 humidified incubator

Randomisation will be carried out by the clinical trial pharmacy service at the trial site

[DOI] [PubMed] [Google Scholar] 41.Epstein J.B., Silverman S., Paggiarino D.A., Jr., Crockett S., Schubert M.M., Senzer N.N., Lockhart P.B., Gallagher M.J., Peterson D.E., Leveque F.G

fistulosum have been found effective against fungal pathogens (77)