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Enzymes for converting TML to butyrobetaine are expressed in most tissues, including the liver, kidneys, muscle, heart, and brain
The study reported DNMT1 inhibition and depletion of SAM levels at doses, which had minimal effect on cell proliferation

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The unexplained nature of idiopathic male infertility may be attributable to intricate genetic and molecular factors, microbial infections in the genital tract, or environmental interactions that remain to be fully elucidated, as evidenced by the observations reported by Wang et al [19]

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