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Description
Recently, it was reported that the ceramide hydrolase alkaline ceramidase (Acer)2 is a novel downstream target molecule of hypoxia-inducible factor (HIF)-2 [19]
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Considering the studies on the relationship between collagen, ECM, and MMPs, we can think any endogenous or exogenous substance that affects these mechanisms may cause recurrence after hernia repair, especially following suture repairs
Originally discovered in human plasma in the 1970s, GHK-Cu is recognized for its roles in wound healing, collagen synthesis, and tissue repair
