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These mechanisms seem to be, at least in part, mediated through the modulation of the GH/IGF-1/insulin system

Zhou ZD, Saw WT, Ho PGH, Zhang ZW, Zeng L, Chang YY, et al

doi: 10.1016/0167-4838(89)90158-1

Glucagon-like peptide-1 receptor (GLP-1 receptor) agonists), such as liraglutide and semaglutide (111), mimic the action of endogenous GLP-1 to increase insulin secretion, suppress glucagon secretion, delay gastric emptying, and promote weight loss

Alternative models of developmental and reproductive toxicity in pharmaceutical risk assessment and the 3Rs
