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Isotope tracing studies have confirmed that the majority of ammonia in the TME is derived from the amino group of glutamines ( Figure 3 Ammonia clearance is essential for maintaining cellular homeostasis and supporting growth and proliferation

doi: 10.1186/1472-6874-14-93 205 GhowsiMKhazaliHSisakhtnezhadS

Some may continue to have symptoms to some degree, while others might recover fully

Davies, B.M., Mowforth, O., Wood, H., Karimi, Z., Sadler, I., Tetreault, L., Milligan, J., Wilson, J.R.F., Kalsi-Ryan, S., Furlan, J.C., Kawaguchi, Y., Ito, M., Zipser, C.M., Boerger, T.F., Vaccaro, A.R., Murphy, R.K.J., Hutton, M., Rodrigues-Pinto, R., Koljonen, P.A., Harrop, J.S., Aarabi, B., Rahimi-Movaghar, V., Kurpad, S.N., Guest, J.D., Wilson, J.R., Kwon, B.K., Kotter, M.R.N., Fehlings, M.G.: Improving Awareness Could Transform Outcomes in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 1]

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