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This means that even if you do have a vitamin B12 deficiency, your body will likely be able to compensate for this at least from a methylation perspective via your dietary choices

If you have a vitamin B12 deficiency, injections are the best option because they bypass the GI tract, where the body loses some of the vitamin from oral supplements

doi: 10.1016/j.immuni.2021.07.005

If the diagnosis of neuropsychological manifestations of vitamin B12 deficiency is delayed, symptoms may become irreversible [7,8,9] within variable time intervals (months to years), depending on residual B12 stores in the liver

J Pharmacol Sci 108(1):717 Cesarec V, Becejac T, Misic M, Djakovic Z, Olujic D, Drmic D et al (2013) Pentadecapeptide BPC 157 and the esophagocutaneous fistula healing therapy