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Importantly, NO generated by iNOS inhibits the polarization of M1-type macrophages to M2-type macrophages induced by interleukin-4 (IL-4) [32]

"Best" is not established, because head-to-head human data does not exist

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A proposal regarding reporting of in vitro testing results

Therefore, optimizing gut health through a balanced diet, a healthy lifestyle, and targeted supplementation becomes essential, especially for women looking for menopause gut health supplements, probiotics for hormonal balance, and broader GLP-1 microbiome support during this transition
