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Watt MJ

NRF2 plays a critical role in this process by upregulating the expression of genes involved in the synthesis of -GC, thereby increasing the overall production of GSH [34]

Specifically, chondrocytes exposed to ferric ammonium citrate (FAC) exhibit increased expression of FTH1 and reduced levels of transferrin receptor 1 (TfR1) and hepcidin, whereas ferroportin (FPN1) expression remains unchanged (38)

Both types of antioxidants participate in the process of scavenging ROS (oxidants)
Thc mc ung glutathione c ni mn khng c gii p ch tit trong bi vit
