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The diagnosis of HIT is hampered by the absence of a validated biomarker and relies on the clinical evaluation, specifically, the response to a low histamine diet and reintroduction of restricted foods

Chronic conditions like long-standing GERD may benefit from extended 8 to 12 week protocols

427 A preliminary clinical study involving five patients with platinum-resistant high-grade epithelial ovarian cancer receiving a combination of carboplatin and Trientine indicated that Trientine can partially reverse the resistance of cancer cells to platinum therapy, warranting further evaluation in larger studies

Prediction of incident diabetic neuropathy using the monofilament examination: a 4-year prospective study

2016;106:1420-1431.e7