Glutathione Metabolism - an overview
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Description
Mutations identified in patients with defective lipoic acid metabolism affect genes involved in the synthesis of iron-sulfur clusters and genes coding for lipoic acid synthetase ( LIAS ), lipoyl transferase 1 ( LIPT1 ), and dihydrolipoamide dehydrogenase (E3 component of -ketoacid dehydrogenase complexes
Prior to analysis 16 L of aqueous metabolite extract was mixed with 8 L phase B (90% acetonitrile, 0.2% formic acid, 10 mM ammonium formate), 5 L of this solution was injected
Department of Dermatology, St
Arterioscler Thromb
Biological systems are not additive
