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Apoptosis After binding to the DNA, the core downstream events platinum agents triggered is apoptosis, which is also called programmed cell death

doi: 10.1096/fj.202100451R

Discussion Given that articular cartilage has limited regenerative potential, once osteoarthritis is established, it becomes irreversible 36,37 , making invasive therapy such as total knee arthroplasty

Ethics declarations Ethics approval and consent to participate All procedures for animal studies were reviewed and approved by the Institutional Animal Care and Use Committee (lACUC), ZJCLA (Approval number: ZJCLA-IACUC-20020099)