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Description

ROS can lead to lipid peroxidation, a process where free radicals attack and damage lipids in cell membranes

In a short, aerobic exercise benefits to cardiorespiratory function and blood circulation, boosting oxygen and nutrient delivery to tissues and enhancing antioxidant defenses

Therefore, ROS levels are reported as raw RLU to represent the total cumulative oxidative burden generated by the treatments within the niche

ACTL6A is found to be critical for regulating the glutathione (GSH) metabolism pathway because it upregulates -glutamyl-cysteine ligase catalytic subunit (GCLC) expression, thereby reducing reactive oxygen species (ROS) levels and inhibiting ferroptosis, a regulated form of cell death driven by the accumulation of lipid-based ROS