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Patients often report noticeable improvements in energy, concentration, and exercise tolerance within weeks of treatment

Cell metabolisms, such as cell growth, cell division, and cell death, are induced

When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes

Oxidant sensing by reversible disulfide bond formation