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Evidence has shown that L-carnitine can promote mitochondrial biogenesis by upregulating peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1), a master regulator of mitochondrial biogenesis [14] and that L-carnitine promotes mitochondrial protein acetylation, a chemical modification that improves mitochondrial function and protects against stressors

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doi: 10.7399/fh.10976, PMID: [DOI] [PubMed] [Google Scholar] 42.Crill CM, Storm MC, Christensen ML, Hankins CT, Bruce Jenkins M, Helms RA