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At doses that reliably release GH, it does not meaningfully raise ACTH, cortisol, prolactin, FSH, LH or TSH a sharp contrast to older secretagogues like GHRP-2 and GHRP-6, which stimulate GH release but also disturb the broader hypothalamic-pituitary-adrenal axis

Clinical studies have used a range of dosages, typically 100300 mg per day

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& Jang, H.-J

In the adrenal cortex and gonads, NADPH is utilized for cholesterol and hormone synthesis
