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Description
NRF2 knockdown in human intestinal epithelial cells (HIEC) led to activation of the cGAS-STING pathway and exacerbated DNA damage

2 The minimal criteria suggestive of vEDS according to the 2017 nosology are a family history of the disorder with a documented causative variant in COL3A1 , a clinical history of arterial rupture, dissection or aneurysm under the age of 40, unexplained sigmoid colon rupture, uterine rupture, or a carotid-cavernous fistula

Melasma requires oral tranexamic acid alongside laser

The most common are gastrointestinal, such as: nausea diarrhea vomiting reflux constipation Many of these symptoms resolve in time

10.1186/s12870-017-1169-1 37 JinJ
