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Clearly, although serum B12 is the most frequently used biomarker of B12 status, the marked variation in the literature for the reference limits and cutoffs said to be indicative of inadequate B12 status, make the diagnosis of B12 deficiency and the provision of prevalence estimates based on serum B12 alone challenging

A central issue is the normalization of symptoms, both by patients and healthcare providers

Life Sci, 88 (11-12) (2011), pp

But it still goes to show you the power of methyl B12 among all vitamin B12 forms

At Perfect B it is used only under supervision, is not FDA approved for these uses, and is not appropriate for tested or competitive athletes