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These globular proteins have an N-terminal domain that consists of a mixture of alpha-helices and beta strands, while the C-terminal domain is all-helical

However, existing medical methods (e.g., antidepressants) have a response rate of only 50% in MDD patients (6), and early clinical symptoms of depression (e.g., anhedonia, sleep disturbance) are often ignored, further worsening health outcomes

Sens Actuators, B Chem 273:16351639

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