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Caffeic acid phenethyl ester attenuates pro-inflammatory and fibrogenic phenotypes of LPS-stimulated hepatic stellate cells through the inhibition of NF-B signaling

The New England Journal of Medicine, 387 (20), 18551864

After a laparotomy, the ovaries were gently removed (a procedure known as a bilateral oophorectomy)

Since damaged mitochondria are a significant source of ROS, preventing their autophagic removal may help maintain mitochondrial fitness and reduce pro-ferroptotic oxidative stress signals (109) ( Figure 5 )

Inclusion criteria Age 18 years, diagnosis of MDD based on DSM-5 diagnostic criteria through a clinical interview with a psychiatrist was included in the study