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Over 400 substances are currently under investigation for their inhibitory capacity of PDE5.[54] For comprehensiveness of this review, we choose to discuss only those compounds that have at least completed phase II testing

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Compared to the control group, ATZ significantly reduced sperm cell concentration (3.06-fold, Table S1), as well as percentages of sperm cell motility (2.97-fold) and viability (2.97-fold) while increasing the percentages of sperm cell abnormalities (5.67-fold) ( P 0.05)

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