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Synthesizing these findings, CBD regulates macrophage polarization by reducing pro-inflammatory M1 phenotypes, affecting TNF- secretion, and inhibiting NO production through eNOS/iNOS pathways

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For example, the turnover rate of each surface iron atom in a 300-nm Fe 3 O 4 nanozyme ( k cat = 9.2 10 3 s 1 ) is five orders of magnitude lower than that of HRP ( k cat = 4.0 10 3 s 1 ), while the turnover rate of a single-particle ( k cat = 3.02 10 4 s 1 ) surpasses that of HRP ( k cat = 4.0 10 3 s 1 ) by 7.55 times 28,83

The following considerations can be underlined, taking into account this controversy and the results obtained from this review: (i) According to the results analyzed here, NAC is preferentially used instead of l-Cys