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You might be at greater risk of RLS if you are taking several medications that can affect dopamine levels

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Fatigue In those without a vitamin B12 deficiency, there is little indication in the medical literature that B12 supplementation can improve fatigue symptoms

These side effects include: Swelling Diarrhea Skin rashes Itching Muscle weakness or cramps Nausea Vomiting Headache Dizziness Leg pain Fatigue Frequent urge to drink water Increased urination Faster heart rate Common Side Effects of Overdose of Vitamin B12 Some of the side effects of vitamin B12 are very common that may occur irrespective of the form in which you are taking vitamin B12 doses