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[DOI] [PMC free article] [PubMed] [Google Scholar] AlMalki, A

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Use ketoconazole tablets with caution in patients with cardiac disease or other conditions that may increase the risk of QT prolongation including cardiac arrhythmias, congenital long QT syndrome, heart failure, bradycardia, myocardial infarction, hypertension, coronary artery disease, hypomagnesemia, hypokalemia, hypocalcemia, or in patients receiving medications known to prolong the QT interval or cause electrolyte imbalances

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These mechanisms also help to explain why some peoples GI symptoms significantly improve after taking an antibiotic