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2018;28(6):848-865.e6
Geiss K, et al
In a mouse model of streptozotocin-induced diabetes with hyperglycemia, high glucose not only increased neutrophil infiltration but also impaired the activity of peroxisome proliferator-activated receptor (PPAR), a transcription factor for lactoferrin (Ltf) encoded by the PPAR gene
However, in drought conditions, this balance is disturbed due to high levels of ROS, which leads to an increase in oxidative stress and a decrease in antioxidants 9
