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Food & Drug Administration recently assigned Human GRAS status to AOD 9604, meaning it is listed under the Generally Recognized As Safe (GRAS) program
IGF, insulin-like growth factor
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In this comprehensive article well explore what FOXO4-DRI is, how it works, the current pre-clinical evidence, its promise and limitations, comparisons with other senolytic approaches, safety and regulatory considerations, and what the future might hold for integrating this novel peptide into a clinical strategy for healthier ageing