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It may promote abnormal angiogenesis (new blood-vessel growth), raising theoretical concerns in patients with cancer history

While the precise mechanism underlying CD38 upregulation in these pathological conditions and disease models are not fully understood, CD38-mediated NAD + consumption leading to NAD + decline and consequent loss of cellular sirtuin activity appears to be a universal mechanism underlying their pathogenesis 24,31

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The results of a Sculptra butt lift may be less dramatic, and they are temporary