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J Am Vet Med Assoc 213, 1426-1427

doi: 10.1104/pp.01018

Medium-term effects (weeks 4-12) What to expect: Progressive improvement for responders

Reported Adverse Effects From the limited human studies and anecdotal reports from users, the following side effects have been documented: Injection site pain and local reactions Joint pain or exacerbation of existing joint discomfort Anxiety and mood disturbances Palpitations and cardiovascular symptoms Insomnia or sleep disruption Nausea and gastrointestinal discomfort The frequency and severity of these effects remain unclear because no systematic adverse effect monitoring has been conducted across a large human population