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La eliminacin se realiza por va renal y es directamente proporcional a la tasa hemtica

10.1016/j.sbi.2015.07.004 [DOI] [PMC free article] [PubMed] [Google Scholar] Flatmark T., Stevens R

Carnitine, Acylcarnitines and Fatty Acid Transport into Mitochondria The substrates for oxidation and most of the energy production in cells are unesterified fatty acids, which originate from three main sources: exogenous fatty acids that enter cells from the circulation, either from the diet or by mobilization from other tissues, those that arise via synthesis de novo from acetyl-CoA, and those released within the cell by the hydrolysis of phospholipids and triacylglycerols

Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis