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In clinical trials, constipation rates with cagrilintide ranged from approximately 10% to 25% depending on the dose, compared to roughly 5% to 8% with placebo

For example, a study conducted by the University of Oxford found that individuals with higher B12 levels had better cognitive function and a lower risk of developing Alzheimers disease

The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown

By reducing inflammation, it might help with chronic conditions such as arthritis and tendinopathy

10.1055/s-0038-1650023 [DOI] [PubMed] [Google Scholar] Cook S