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The only RCTs currently available concern the use of bosentan, but in clinical practice, initial monotherapy with ERA or PD5i for symptomatic patients is proposed

Engineered with C-terminal truncation, the tHFn(+) nanocarrier promotes pH-responsive disassembly in the endosomal milieu (pH ~ 6.06.5), weakening C3C4 subunit interactions as revealed by cryo-EM

Bcl-2 is expressed in human natural killer cells and is regulated by interleukin-2

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Hypoglycemia (low blood sugar) is uncommon in individuals not taking insulin or sulfonylureas
