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Drug Interactions : BPC-157's interaction with nitric oxide pathways and growth hormone receptors raises concerns about interference with medications (Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), anticoagulants, and hormonal therapies)

doi: 10.1136/bmj.j5024

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The evidence base for tirzepatide as monotherapy is robust, with pivotal trials including SURMOUNT-1 demonstrating significant weight reduction in adults with obesity, and SURPASS trials establishing glycemic efficacy in type 2 diabetes

The duration of oral cobalamin therapy required prior to reassessment at this point is unclear, but 30-60 days might be appropriate