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Recently, a randomized, double-blind, placebo-controlled trial in 295 patients with Alzheimers disease found that DHA supplementation (2 grams/day) for 18 months was not effective in slowing cognitive decline (129)

Although elegant and effective for yeast ( Saccharomyces cerevisiae ) grown in specifically controlled media, global isotopic labeling is prohibitively expensive, time-consuming, and practically inapplicable to complex mammalian cell culture models or clinical samples

Relation between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations

Franco R, DeHaven WI, Sifre M, Bortner CD, Cidlowski JA