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It is best to get your nutrients from whole foods and stick with a healthy and balanced diet for weight loss

Certain medications The following drugs can reduce levels of vitamin B12 in your body: Antibiotics -- long-term use can lower vitamin B levels generally Anti-seizure drugs Chemotherapy medicines, especially methotrexate Drugs used to reduce stomach acid, like H2 blockers (Pepcid AC, Tagamet, Zantac) and proton pump inhibitors (Nexium, Prevacid, Prilosec) Metformin (Glucophage) -- taken for diabetes Colchicine -- taken for gout Some cholesterol-lowering medications Other causes You're over 65

Ask about common gastrointestinal issues (nausea, vomiting, diarrhea) and rarer risks like gallbladder disease or pancreatitis (FDA Wegovy prescribing information)

Mood Regulation Finally, vitamin B12 is linked to improved mood

5-Amino-1MQ functions as a competitive inhibitor at the nicotinamide substrate site of NNMT, with an IC50 of 1.2 M against human NNMT