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The mTOR complex is a sensor of cellular nutrients, and activation of mTOR signaling in pancreatic cells leads to cell mass expansion, increased glucagon content, and enhanced glucagon secretion, while suppression of mTOR signaling results in the opposite effect 45,46

Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB,

doi: 10.1039/C6RA20282A

Elevations in lipase and amylase levels are commonly seen, often without clinical signs of pancreatitis, making interpretation challenging
