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A large 2022 New Zealand cohort study (N = 31,907) demonstrated that, among males with gout and no history of CVD, regular urate-lowering medicine dispensing and treatment of serum urate to target levels was associated with a lower risk of cardiovascular events

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Furthermore, the uniform concentration profile across the bloodstream minimizes spatial variability, thereby avoiding the sampling-dependent gradients that frequently complicate ISF-based sensing modalities

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