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The differences in host trees and the evolutionary distances between these Xanthophyllomyces species from the northern and southern hemispheres suggest that they have been strongly influenced by the ancient continental separation of the Earth, which is of great interest from an Earth science perspective [211]

They are integral to numerous physiological processes, encompassing glucose and lipid metabolism, insulin resistance, and mitochondrial function, thereby rendering them pivotal factors in the etiology of conditions such as type 2 diabetes, obesity, and NAFLD [107,144,145]

Targeted therapy for hepatocellular carcinoma

Compared to the liver, we observed that the kidney has: (1) similar increased use of energy-related metabolites and production of urea cycle and ammonia-related intermediates, suggesting a shared catabolism in AKI, and (2) higher pools of energy metabolism intermediates in AKI
