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This margin of safety provides reassurance, though caution remains appropriate given the limited formal human studies

Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin)

Many studies have administered doses ranging from 250 mg to 1,000 mg per day
doi: 10.1016/j.nano.2014.09.014
Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ
